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Prolozone Specialist

Alternative Physical Medicine of Colorado

Alternative Medicine & Chiropractor located in Littleton, CO

Prolozone™ is an injectable treatment that dramatically reduces inflammation and eases your pain, no matter where it is or what causes it. At Alternative Physical Medicine of Colorado, in Littleton, Colorado, Ron Spallone, DC, has extensive experience using Prolozone to help patients get exceptional pain relief, including a long-lasting reprieve from chronic pain that doesn’t respond to conservative medical treatments. To learn if you’re a candidate for Prolozone, schedule an appointment online or call the office today.

Prolozone Q & A

What is Prolozone?

Prolozone is an injectable treatment that contains a potent form of oxygen called ozone. Your body must have the right amount of oxygen to regenerate the new tissues needed for healing.

When wounds don’t get enough oxygen, and they’re slow to heal, Prolozone delivers a boost of ozone that:

  • Relieves your pain
  • Reduces inflammation
  • Energizes cells
  • Triggers tissue regeneration
  • Accelerates healing
  • Boosts circulation
  • Stimulates growth factors
  • Strengthens the immune system
  • Increases oxygen use inside cells


Your Prolozone injection also contains a local anesthetic, anti-inflammatory medications, and vitamins and minerals that support healing and improve oxygen utilization inside cells.

Since ozone is a gas, it expands to cover the surrounding area. No matter where your provider injects Prolozone, it thoroughly treats the damaged tissues.

What conditions improve with Prolozone?

Many problems that cause pain can improve with Prolozone, as it stimulates new tissue growth, even for tissues that don’t heal on their own, like cartilage. 

A few examples of conditions often treated with pain include:

  • Neck pain
  • Whiplash
  • Herniated discs
  • Degenerated discs
  • Low back pain
  • Plantar fasciitis
  • Tendon tears
  • Sciatica
  • Neuropathy
  • Rotator cuff tears
  • Knee injuries
  • Osteoarthritis


The team at Alternative Physical Medicine of Colorado may recommend Prolozone for sports injuries and any musculoskeletal problem that causes pain in your hip, knee, or other joints.

What happens during my Prolozone treatment?

Before you get a Prolozone injection, your provider at Alternative Physical Medicine of Colorado reviews your medical history and symptoms, completes a physical examination, and performs diagnostic ultrasound if needed.

If they determine that you need a Prolozone injection, you simply relax while having the procedure. The injection causes little to no pain because they use a fine needle and apply a topical numbing cream.

You may have slight soreness afterward at the site of your injection. Otherwise, side effects seldom occur.

Ozone quickly reduces the production of biochemicals that cause inflammation. As a result, many people notice an improvement in their pain after one injection.  

Though one injection makes a difference, you will probably need several spaced about two weeks apart to achieve optimum results. After completing a series of Prolozone treatments, you should have long-lasting pain relief. 

To learn if you’re a good candidate for Prolozone, call the office or book an appointment online today.